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	<title>Comments on: Aspartame Safety and Internet Urban Legends</title>
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	<link>http://www.theness.com/neurologicablog/?p=43</link>
	<description>Your Daily Fix of Neuroscience, Skepticism, and Critical Thinking</description>
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		<title>By: mjeppsen</title>
		<link>http://www.theness.com/neurologicablog/?p=43&#038;cpage=1#comment-1250</link>
		<dc:creator>mjeppsen</dc:creator>
		<pubDate>Fri, 15 Feb 2008 19:42:06 +0000</pubDate>
		<guid isPermaLink="false">http://www.theness.com/neurologicablog/?p=43#comment-1250</guid>
		<description>Thanks for posting on this, Steven. I noted today what looks like a new study (2008.02.15?) with rats that showed some pretty dreadful results of the sweetener: http://www.myaspartameexperiment.com

I&#039;m no scientist, but the methods of the study seem to be pretty rigorous at first glance. Some analysis here: http://www.medkb.com/Uwe/Forum.aspx/cancer/3292/30-female-pet-store-rats-drinking-lifelong-13-5-mg-aspartame-1-3

I&#039;m curious what you folks think of this info and if you think it will have any effect (either way) on the current consensus of the scientific community.

-MJ</description>
		<content:encoded><![CDATA[<p>Thanks for posting on this, Steven. I noted today what looks like a new study (2008.02.15?) with rats that showed some pretty dreadful results of the sweetener: <a href="http://www.myaspartameexperiment.com" rel="nofollow">http://www.myaspartameexperiment.com</a></p>
<p>I&#8217;m no scientist, but the methods of the study seem to be pretty rigorous at first glance. Some analysis here: <a href="http://www.medkb.com/Uwe/Forum.aspx/cancer/3292/30-female-pet-store-rats-drinking-lifelong-13-5-mg-aspartame-1-3" rel="nofollow">http://www.medkb.com/Uwe/Forum.aspx/cancer/3292/30-female-pet-store-rats-drinking-lifelong-13-5-mg-aspartame-1-3</a></p>
<p>I&#8217;m curious what you folks think of this info and if you think it will have any effect (either way) on the current consensus of the scientific community.</p>
<p>-MJ</p>
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		<title>By: verena_do</title>
		<link>http://www.theness.com/neurologicablog/?p=43&#038;cpage=1#comment-695</link>
		<dc:creator>verena_do</dc:creator>
		<pubDate>Thu, 13 Dec 2007 15:24:29 +0000</pubDate>
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		<description>Thank you for addressing this issue.  The idea that aspartame is really bad for you/causes brain tumors/causes MS etc. seems remarkably persistent.  I periodically do a check on Medline and so far have found nothing that would discourage me from drinking diet soda.  I suspect there is some moralism behind the ideology...</description>
		<content:encoded><![CDATA[<p>Thank you for addressing this issue.  The idea that aspartame is really bad for you/causes brain tumors/causes MS etc. seems remarkably persistent.  I periodically do a check on Medline and so far have found nothing that would discourage me from drinking diet soda.  I suspect there is some moralism behind the ideology&#8230;</p>
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		<title>By: ruralmysteries</title>
		<link>http://www.theness.com/neurologicablog/?p=43&#038;cpage=1#comment-456</link>
		<dc:creator>ruralmysteries</dc:creator>
		<pubDate>Thu, 08 Nov 2007 21:30:39 +0000</pubDate>
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		<description>The anti-aspartame Web sites like to cite FAA cautions that pilots not drink diet soda on-the job and an article warning against aspartame that appeared in General Aviation News.  &lt;a href=&quot;http://www.generalaviationnews.com/editorial/articledetail.lasso?-token.key=8738&amp;-token.src=column&amp;-nothing&quot; rel=&quot;nofollow&quot;&gt;Neither is true&lt;/a&gt;.</description>
		<content:encoded><![CDATA[<p>The anti-aspartame Web sites like to cite FAA cautions that pilots not drink diet soda on-the job and an article warning against aspartame that appeared in General Aviation News.  <a href="http://www.generalaviationnews.com/editorial/articledetail.lasso?-token.key=8738&amp;-token.src=column&amp;-nothing" rel="nofollow">Neither is true</a>.</p>
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		<title>By: Steven Novella</title>
		<link>http://www.theness.com/neurologicablog/?p=43&#038;cpage=1#comment-443</link>
		<dc:creator>Steven Novella</dc:creator>
		<pubDate>Tue, 06 Nov 2007 18:17:21 +0000</pubDate>
		<guid isPermaLink="false">http://www.theness.com/neurologicablog/?p=43#comment-443</guid>
		<description>rtnmtn,

You make good points, but I think you are premature and unfair in your accusation of &quot;very apparent bias.&quot; I have no bias of which I am aware on this issue. I simply was reporting the consensus opinion. I did not discount the Italian study - it is evidence, the methods seem valid, etc. I simply pointed out that the weight of the literature is negative, and every formal review of the literature has reached this same conclusion. More studies may move the evidence in the direction of a connection, we can only wait and see. 

My choice of links is often based in what I can find with the time I have. Putting out a blog like this 4-5 times a week does not afford impeccable attention to detail. To balance this, however, blogs are also not written in stone - so I can add more or better references, or address questions or vague points that readers bring up. It&#039;s the nature of this medium. So don&#039;t read too much into my choice of reference links.</description>
		<content:encoded><![CDATA[<p>rtnmtn,</p>
<p>You make good points, but I think you are premature and unfair in your accusation of &#8220;very apparent bias.&#8221; I have no bias of which I am aware on this issue. I simply was reporting the consensus opinion. I did not discount the Italian study &#8211; it is evidence, the methods seem valid, etc. I simply pointed out that the weight of the literature is negative, and every formal review of the literature has reached this same conclusion. More studies may move the evidence in the direction of a connection, we can only wait and see. </p>
<p>My choice of links is often based in what I can find with the time I have. Putting out a blog like this 4-5 times a week does not afford impeccable attention to detail. To balance this, however, blogs are also not written in stone &#8211; so I can add more or better references, or address questions or vague points that readers bring up. It&#8217;s the nature of this medium. So don&#8217;t read too much into my choice of reference links.</p>
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		<title>By: Cay</title>
		<link>http://www.theness.com/neurologicablog/?p=43&#038;cpage=1#comment-433</link>
		<dc:creator>Cay</dc:creator>
		<pubDate>Tue, 06 Nov 2007 02:29:14 +0000</pubDate>
		<guid isPermaLink="false">http://www.theness.com/neurologicablog/?p=43#comment-433</guid>
		<description>I heard the interview of Devra Davis too.  And like you all, she got me wondering about her legitimacy.  She seems to have that combination of credentials and credulity that leads people astray.

And a comment on aspartame.  A friend once told me that she gets regular soda for her kids instead of diet because &quot;you don&#039;t know what the sweetener is going to do to you.&quot;   I still wish I&#039;d responded &quot;Yeah unlike regular soda, which we know can give you obesity and diabetes.&quot;</description>
		<content:encoded><![CDATA[<p>I heard the interview of Devra Davis too.  And like you all, she got me wondering about her legitimacy.  She seems to have that combination of credentials and credulity that leads people astray.</p>
<p>And a comment on aspartame.  A friend once told me that she gets regular soda for her kids instead of diet because &#8220;you don&#8217;t know what the sweetener is going to do to you.&#8221;   I still wish I&#8217;d responded &#8220;Yeah unlike regular soda, which we know can give you obesity and diabetes.&#8221;</p>
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		<title>By: abartley</title>
		<link>http://www.theness.com/neurologicablog/?p=43&#038;cpage=1#comment-428</link>
		<dc:creator>abartley</dc:creator>
		<pubDate>Mon, 05 Nov 2007 21:36:19 +0000</pubDate>
		<guid isPermaLink="false">http://www.theness.com/neurologicablog/?p=43#comment-428</guid>
		<description>I almost asked about your views concerning aspartame on the Skeptic&#039;s Guide website a few weeks ago.  The ms/lupus and the cancer email have both been posted in the general staff inbox at my work.  I have tackled it and discusses the poorly presented evidence that this email purports to have.  Although the New Age counselor who sent it out maintains the belief, I do believe I was able to help alleviate some fears of those who were being swayed by the letter.  The year before the same counselor sent out the aspartame is causing cancer letter.  This was the first letter where I felt comfortable enough to challenge the info and really won some support among the faculty for my skepticism and evidence-based thinking.</description>
		<content:encoded><![CDATA[<p>I almost asked about your views concerning aspartame on the Skeptic&#8217;s Guide website a few weeks ago.  The ms/lupus and the cancer email have both been posted in the general staff inbox at my work.  I have tackled it and discusses the poorly presented evidence that this email purports to have.  Although the New Age counselor who sent it out maintains the belief, I do believe I was able to help alleviate some fears of those who were being swayed by the letter.  The year before the same counselor sent out the aspartame is causing cancer letter.  This was the first letter where I felt comfortable enough to challenge the info and really won some support among the faculty for my skepticism and evidence-based thinking.</p>
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		<title>By: ziggy</title>
		<link>http://www.theness.com/neurologicablog/?p=43&#038;cpage=1#comment-418</link>
		<dc:creator>ziggy</dc:creator>
		<pubDate>Sun, 04 Nov 2007 07:31:52 +0000</pubDate>
		<guid isPermaLink="false">http://www.theness.com/neurologicablog/?p=43#comment-418</guid>
		<description>I&#039;m one of those who get headaches from aspartame.  It takes about 10 - 15 minutes to kick in.  I&#039;m not sure if I&#039;d call it a migraine, but there is some light sensitivity with it.

On a different note:  I used to work as a research assistant for a biochemistry professor.  I can&#039;t remember the details but he pointed out a metabolic pathway in the eye (his specialty) where aspartame could be metabolized with one of the metabolites being methanol.  Methanol, of course, is NOT something you want in your eye!  I&#039;m not sure if aspartame would ever reach the eye (there is a blood/eye barrier much like the blood/brain barrier), nonetheless he would never touch the stuff and discouraged others from using it.</description>
		<content:encoded><![CDATA[<p>I&#8217;m one of those who get headaches from aspartame.  It takes about 10 &#8211; 15 minutes to kick in.  I&#8217;m not sure if I&#8217;d call it a migraine, but there is some light sensitivity with it.</p>
<p>On a different note:  I used to work as a research assistant for a biochemistry professor.  I can&#8217;t remember the details but he pointed out a metabolic pathway in the eye (his specialty) where aspartame could be metabolized with one of the metabolites being methanol.  Methanol, of course, is NOT something you want in your eye!  I&#8217;m not sure if aspartame would ever reach the eye (there is a blood/eye barrier much like the blood/brain barrier), nonetheless he would never touch the stuff and discouraged others from using it.</p>
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		<title>By: matt g</title>
		<link>http://www.theness.com/neurologicablog/?p=43&#038;cpage=1#comment-417</link>
		<dc:creator>matt g</dc:creator>
		<pubDate>Sun, 04 Nov 2007 03:07:52 +0000</pubDate>
		<guid isPermaLink="false">http://www.theness.com/neurologicablog/?p=43#comment-417</guid>
		<description>Hey Steven,

Thanks for posting this. I remember when I was first diagnosed with MS in 2005, it took about a month before my (well meaning) father encountered and forwarded me the Aspartame scare chain email.</description>
		<content:encoded><![CDATA[<p>Hey Steven,</p>
<p>Thanks for posting this. I remember when I was first diagnosed with MS in 2005, it took about a month before my (well meaning) father encountered and forwarded me the Aspartame scare chain email.</p>
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		<title>By: Steven Novella</title>
		<link>http://www.theness.com/neurologicablog/?p=43&#038;cpage=1#comment-414</link>
		<dc:creator>Steven Novella</dc:creator>
		<pubDate>Sat, 03 Nov 2007 12:30:16 +0000</pubDate>
		<guid isPermaLink="false">http://www.theness.com/neurologicablog/?p=43#comment-414</guid>
		<description>Paul,

I agree that what you describe is how conspiracy theorists in general (and this case also) arrive at their conclusions. But that is not how they justify their conclusions. I was addressing the logic by which she justifies her conspiracy conclusion. 

And I do think it is an argument from final consequence - a subtype related to the &quot;cui bono&quot; or &quot;who benefits&quot; subtype? The argument is that if someone benefits from some thing then they caused the thing. The conspiracy argument is the flip side of this - if someone would be harmed by something then they are engaged in a conspiracy to cover it up. Both subtypes are dependent upon final consequences, so I think they are subtypes of this fallacy.</description>
		<content:encoded><![CDATA[<p>Paul,</p>
<p>I agree that what you describe is how conspiracy theorists in general (and this case also) arrive at their conclusions. But that is not how they justify their conclusions. I was addressing the logic by which she justifies her conspiracy conclusion. </p>
<p>And I do think it is an argument from final consequence &#8211; a subtype related to the &#8220;cui bono&#8221; or &#8220;who benefits&#8221; subtype? The argument is that if someone benefits from some thing then they caused the thing. The conspiracy argument is the flip side of this &#8211; if someone would be harmed by something then they are engaged in a conspiracy to cover it up. Both subtypes are dependent upon final consequences, so I think they are subtypes of this fallacy.</p>
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		<title>By: Nathan Mahoney</title>
		<link>http://www.theness.com/neurologicablog/?p=43&#038;cpage=1#comment-412</link>
		<dc:creator>Nathan Mahoney</dc:creator>
		<pubDate>Sat, 03 Nov 2007 02:58:26 +0000</pubDate>
		<guid isPermaLink="false">http://www.theness.com/neurologicablog/?p=43#comment-412</guid>
		<description>It&#039;s possible that people are confusing or conflating aspartame with saccharin, which does indeed have a carcinogenic profile--in rats, but not humans. 

Remember this warning stamped over anything containing saccharin: &quot;Use of this product may be hazardous to your health. This product contains saccharin, which has been determined to cause cancer in laboratory animals.&quot; For years people were reading that warning, 1977-2000 (the warning has since been removed in light of human epidemiological studies). It&#039;s perfectly reasonable for someone to assume that cancer in laboratory animals means a good chance of cancer in humans. That&#039;s 13+ years of bad press. It&#039;s difficult for people to forget what they&#039;ve known for so long and be re-educated to the contrary opinion, whatever the evidence or the individual&#039;s skeptical composition*. Moreover, even after being (re)taught, people often regress to their earlier misconceptions. This is well-documented in the education literature.

*This does not explain the crackpots, but I bet it does explain the majority of the populace. Of course all the crap on the interweb doesn&#039;t help matters, as Steve says. The best we can do for the masses is get the correct information out there in as many places as possible. It&#039;s more about marketing than logic and evidence.</description>
		<content:encoded><![CDATA[<p>It&#8217;s possible that people are confusing or conflating aspartame with saccharin, which does indeed have a carcinogenic profile&#8211;in rats, but not humans. </p>
<p>Remember this warning stamped over anything containing saccharin: &#8220;Use of this product may be hazardous to your health. This product contains saccharin, which has been determined to cause cancer in laboratory animals.&#8221; For years people were reading that warning, 1977-2000 (the warning has since been removed in light of human epidemiological studies). It&#8217;s perfectly reasonable for someone to assume that cancer in laboratory animals means a good chance of cancer in humans. That&#8217;s 13+ years of bad press. It&#8217;s difficult for people to forget what they&#8217;ve known for so long and be re-educated to the contrary opinion, whatever the evidence or the individual&#8217;s skeptical composition*. Moreover, even after being (re)taught, people often regress to their earlier misconceptions. This is well-documented in the education literature.</p>
<p>*This does not explain the crackpots, but I bet it does explain the majority of the populace. Of course all the crap on the interweb doesn&#8217;t help matters, as Steve says. The best we can do for the masses is get the correct information out there in as many places as possible. It&#8217;s more about marketing than logic and evidence.</p>
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